Burkholderia cepacia, one of the bacterial species found on the potable water dispenser on the International Space Station (Image credit Janice Haney Carr USCDCP) It turns out that bacteria "SPICE" often stands for the following bacterial species Serratia spp, Providencia spp, indolepositive Proteae (eg Proteus spp not mirabilis, Morganella spp, Providencia spp), Citrobacter spp, and Enterobacter spp Some have also included Pseudomonas spp ("P")Start studying Bacterial Classes Learn vocabulary, terms, and more with flashcards, games, and other study tools

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Space bugs bacteria- Bacteria flown on the space shuttle mutated in ways that made them nearly three times more deadly to mice, a new study finds While the bugs Deadly space bugs It is known that microgravity (MG) affects the way cells react For example, astronauts coming back to Earth after a long time spent under very low gravity show signs of bone resorption and muscle mass loss




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Space flight turns Salmonella into superbug By Ed Yong Published The infected mice succumbed to much lower concentrations of spacefaring bacteria and in much shorter times "The six bad bugs we call the ESKAPE bacteria—Enterococcus faecium, Staphylococcus aureus, Klebsiella species, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species—are New Bacterial LifeForm Discovered in NASA and ESA Spacecraft Clean Rooms High atop a platform inside a clean room at the European Space Two years earlier this same bug had surfaced 4,000
The International Space Station is infested with mysterious and potentially dangerous space bugs Comment 'Given the multidrug resistance results for these bacteria and the increased In one of the first major breakthroughs in drugs from bugs space, Seres Therapeutics MCRB, 248% has recently made major strides toward marketing the first ever microbiomebased therapy It's for SPACE BUGS Bacterial superbugs hitched a ride on the International Space Station NASA researchers said there's still more to learn about how the bacteria might react in space conditions
Superbugs have colonized the International Space Station—but there's a silver lining by Frontiers Credit CC0 Public Domain Astronauts leave behind many things when they boldly go Bacteria Even more concerning were the colonies of organisms attacking the rubberised seals around the space station windows and the acidexcreting bugs slowly eating the electrical cablingUS BioSatellite Program In the late 1960's researchers discovered that bacteria grow better in space




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The group observed phenotypic changes between the E coli grown in space and the same strain grown on earth They observed a 13fold increase in final cell count in space, meaning the bacteria grew faster and denser than on earth The space cultivated E coli developed resistance to normally inhibitory levels of the antibiotic, gentamicin sulfate Research has revealed the bug infestation on the ISS is actually bacteria and fungus Not only could the bacteria make astronauts ill, but they may also be dangerous for the space station'sBind to bacterial DNAgyrase and interfere with DNA replication active against broad range of bacteria including Enterobacteriaceae, N gonorrhea, H flu, M catarrhalis, pseudomonas, C trachomatis, mycoplasma and variable activity against staph and strep some synergy with betalactams Ciprofloxacin (po, IV – Cipro)



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SPACE bugs = Serratia marcescens, Pseudomonas aeruginosa, Acinetobacter baumannii, Citrobacter freundii, Enterobacter spp Macrolides Erythromycin, azithromycin, clarithromycin GI upset (nausea, vomiting, diarrhea) QT prolongation Inhibits 3A (ery > clari >> azi) QT prolongation risk = ery >> clari > azi Glycopeptides Vancomycin Red man syndrome Every year, scientists discover thousands of new species on Earth — everything from monkeys to microbes Now, astronauts have discovered a new species of bacteria in space — and scientists think the bugs could one day help people grow plants on Mars Can We Grow Plants on Mars? Bugs and Drugs The best starting point is knowing what drugs cover what bugs This is admittedly daunting So I recommend prioritizing Let me be clear by saying that the more you know the better off you'll be That said, we both know you're here because you have a test tomorrow and time is a factor




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Since 06, Nickerson has completed five bacteria experiments in space, and she just got funding for two more In her bioreactors on Earth, which create lowfluidshear conditions, Nickerson hasThe increased susceptibility ofAmong Gramnegative bacteria, the emergence of resistance to extendedspectrum cephalosporins has been a major concern It appeared initially in a limited number of bacterial species (E cloacae, C freundii, S marcescens, and P aeruginosa) that could mutate to hyperproduce their chromosomal class C βlactamase




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SQ 26,776) is the first member of a new class of betalactam antibiotics, the monobactams Aztreonam is selectively active against Gramnegative aerobic bacteria and inactive against Grampositive bacteria Thus, in vitro,(Bugs in the News); THE International Space Station is infested with mysterious space bugs that may be leaving astronauts at risk of 'serious harm', according to a




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Tardigrades (Tardigrada), also known as water bears or moss piglets, are a phylum of small invertebrates They were first described by the German pastor JAE Goeze in 1773 and given the name SPICE (SPACE) Organisms Colloquial acronym for gramnegative bacteria that have inducible, chromosomal betalactamase genes known as AmpC Resistance may not be detectable initially, but appears after a period of exposure to betalactam antibiotics Organisms in this group include • Serratia • Providencia • "Indolepositive" Proteus species / Acinetobacter • The space station is essentially an orbiting lab where hundreds of experiments are carried out every day The zerogravity, or microgravity, environment has already been host to research on bacteria
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The "SPACE" organisms are a group of bacteria that harbor genes within their chromosomes (eg, AmpC), which if expressed, can cause the production of antibioticdestroying betalactamase enzymes The SPACE bugs are Serratia, Pseudomonas, Acinetobacter, Citrobacter, and Enterobacter bacteria (singular bacterium) Singlecelled organisms These dwell nearly everywhere on Earth, from the bottom of the sea to inside other living organisms (such as plants and animals) bacterial Having to do with bacteria, singlecelled organisms These dwell nearly everywhere on Earth, from the bottom of the sea to inside animalsStaphylococcus aureus (MRSA) bacteria 2 Bacteria – such as Staphylococcus aureus which is often found in human skin and noses, possibly causing infections, and Clostridium difficile which can cause severe inflammation of the colon 3




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Woodard is senior author of an article describing way he and his research team genetically modified Escherichia coli bacteria, known as a Gramnegative bug, to weaken its defenses Share FULL Venkateswaran's team has found undiscovered bacteria from the ISS and on Earth, in space vehicle assembly rooms The fact that those are also referred to as "clean rooms" should tell you why that'sEcologist Rob Dunn's new book describes the tiny life forms, helpful and risky, that live in different parts of the home, including on floors and in water faucets, basements and heating systems



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NASA's Space Product Development (SPD) program, located at the Marshall Space Flight Center, encourages the commercialization of space by industry through 17 such CSCs Antibiotic links What the Heck is an Antibiotic? When the preliminary cultures resulted as growing GNR's, a fear was that the patient was infected with a "SPACE" bug and so Cefepime was initiated SPACE is a pneumonic to remember the bacteria that are have AmpC betalactamase enzymes encoded onKnow Your Bugs – A Closer Look At Viruses, Bacteria, And Parasites A researcher looking at Ecoli bacteria strain at the Institute of Food Safety, Animal Health and Environment in Latvia Ints




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Gram negative resistance mechanisms are incredibly complex and applying current scientific knowledge to clinical practice is a major challenge To provide insights on this topic, a leading infectious diseases pharmacist with significant experience in this field is interviewed Interview With Conan MacDougall, PharmD, MAS, BCPSAQ ID Interview By Timothy PAntimicrobial resistance (AMR) occurs when microbes evolve mechanisms that protect them from the effects of antimicrobials The term antibiotic resistance is a subset of AMR, as it applies to bacteria that become resistant to antibiotics Resistant microbes are more difficult to treat, requiring higher doses, or alternative medications which may prove more toxicSPACE stands for Serratia, Pseudomonas, Acinetobacter, Citrobacter, Enterobacter This definition appears rarely and is found in the following Acronym Finder categories MLA style "SPACE"




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Klebsiella, Ecoli, other Enterobacteriacea and nonfermenting Gramneg bacteria (SPACE bugs) nosacomial gram neg, pseudomonas and acintobacter Term ESBL is mediated by Definition Plasmids Term Laboratory Detection of ESBL suceptability CP Definition Suceptible 8mcg/ml Intermediate 16 mcg/ml Nickerson and her colleagues sent Salmonella bacteria, which causes food poisoning, to the International Space Station aboard two shuttle flights in Between May 14 and February 15, a drugresistant strain of shigella has infected 243 people across the US, according to the US Centers for Disease Control and Prevention (CDC) The CDC's findings were first published in the agency's Morbidity and Mortality Weekly Report The CDC found that 90 percent of cases of the shigellosis infection analyzed in




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Bugs in space have been something of a riddle through the decades of human spaceflight As the video mentions, it was originally believed that weightlessness would not affect bacteria, or that they may even get stronger in space In recent years, however, scientists have come to think that the opposite is true; The space bugs were found to be three times as deadly to mice as the control bugs Cheryl Nickerson is an Associate Professor at the Centre for Infectious Diseases and Vaccinology at Arizona State The study is funded by the European Space Agency and NASA The goal is to identify which bacteria survive on the antimicrobialcoated areas and to assess the possible health risks for crew members




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One day's worth of meals for an astronaut aboard the International Space Station (ISS) Fresh Air for Nov 12, 18 Counting The Bugs And Bacteria, You're 'Never Home Alone' NPR Older browse past shows Show Archive Newer Monday, Monday's Show Humans would5 Common Superbug Infections Caused by Bacteria Superbugs are strains of bacteria, viruses, parasites, and fungi that are resistant to most of the antibiotics and other medications commonly used to treat the infections that they causeSince the inception of antibiotics, the bacteria they treat have been adapting and changing in order to build up resistance




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The NASA study, lead by microbiologist Nitin Singh, found that the drugresistant space bugs are genetically distinct from the most infectious forms of E bugandensis and therefore do not pose an




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